VP, CMC

Brian Kile is our VP of CMC and has served as the analytical subject matter expert for drug substance and drug product manufacturing across Leal’s pipeline since 2022. Brian received his Ph. D in Analytical Chemistry from University of North Carolina at Chapel Hill where he studied the release of neurotransmitters in disease state models using a variety of analytical techniques. He went on to accumulate experience in different aspects of analytical method development and strategy as a Forensic Examiner with the Federal Bureau of Investigation. Brian began a second career in pharmaceutical manufacturing at Nitto Denko Avecia where he led a team responsible for analytical method development and validation for a multitude of oligonucleotide therapeutic modalities from preclinical to commercial phases